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Persons with occupational risk Persons working with nonhuman primates Persons working with HAV in a research laboratory CDC does not have official guidance to define all subgroups of persons recommended to receive IG. Further clinical guidance should be obtained for patients whose immune status is unclear.
Who requires protection i.
HepA vaccine or IG should be administered to all previously unvaccinated persons who have been exposed or are at risk of exposure due to close personal contacts of persons with serologically confirmed hepatitis A i. Post-exposure prophylaxis PEP should be administered to all previously unvaccinated staff and attendees of child-care centers or homes if 1 one or more cases of hepatitis A is recognized in children or 2 cases are recognized in two or more households of center attendees.
If one or more cases of hepatitis A infection occurs among employees, PEP should be considered based on the duties, hygienic practices and presence of symptoms at work.
In centers that do not provide care to children who wear diapers, PEP may be administered only to care center contacts of the index patient. When an outbreak occurs i.
Persons exposed to a common source, such as an infected food handler. Food handlers are not at increased risk for hepatitis A because of their occupation.
Because common-source transmission to patrons is unlikely, PEP administration to patrons typically is not indicated but may be considered if 1 during the time when the food handler was likely to be infectious, the food handler both directly handled uncooked foods or foods after cooking and had diarrhea or poor hygienic practices, and 2 patrons can be identified and treated within 2 weeks of exposure, though the risk for individual patrons remains low.
If a case of hepatitis A is found in a setting providing services to children or adults, such as a school, hospital, office setting, corrections facility or homeless shelter, what should be done?
PEP is not routinely indicated when a single case occurs in an elementary or secondary school or an office or other work setting, and the source of infection is outside of the setting. When a person who has HAV infection is admitted to a hospital, staff members should not routinely be administered PEP; instead, appropriate infection control practices should be emphasized, i.
PEP should be administered to persons who have close contact with index patients if an epidemiologic investigation indicates HAV transmission has occurred among students in a school or among patients or between patients and staff members in a hospital. PEP should be considered for all previously unvaccinated residents and employees when a confirmed hepatitis A case occurs in a setting where close personal contact occurs regularly and hygiene standards are difficult to maintain e.
In a setting containing multiple enclosed units or sections e. Should hepatitis A vaccine be recommended for individuals displaced by a disaster?
Although hepatitis A vaccine is recommended for all children in the United States at age 1 year i. Persons who evacuate their homes under orderly conditions to a congregate setting where sanitary conditions prevail should not require hepatitis A vaccine as a result of their evacuation status, unless they have been evacuated from an area where exposure to hepatitis A virus is likely or have been exposed to persons with suspected or proven hepatitis A infection.
Other severely immunocompromised persons who have been vaccinated in the past may also benefit from PEP and should be assessed on an individual basis.
Persons who receive routine IG administration for an immunocompromising condition should also be assessed on an individual basis. General Best Practice Guidelines for Immunization Pregnancy Infants born to mothers with HAV infection during pregnancy are usually healthy, but hepatitis A infection during pregnancy has been associated with gestational complications e.Also, check out the Panther Tracks: Your First Term Guide (even if it's your second or third term) to learn more about the resources PCC has to help you succeed.
Web Links There are many internet resources related to the field of clinical laboratory science. Case Studies in Clinical Laboratory Science by Linda Graves Ed.D. MT (ASCP), Elizabeth Gockel-Blessing This unique collection of 55 multidisciplinary case studies is designed to help1/5(3).
The case study method of teaching applied to college science teaching, from The National Center for Case Study Teaching in Science.
"The ASCP Board of Certification (BOC) affirms that an individual demonstrates the knowledge and skills to perform the essential task in the medical laboratory. By using AWS, Unilever was able to migrate web properties in less than 5 months to a standardized digital marketing platform capable of supporting global campaigns, and reducing the .
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